Denny Duquette from Grey’s Anatomy
Cue ugly sobbing. Grey’s Anatomy has seen an ongoing stream of endless tragedies come through the doors of Grey-Sloan Memorial, but one of the hardest-hitting losses was that of Denny Duquette (Jeffrey Dean Morgan). His death came at a time when the casualty count on Grey’s hadn’t yet reached peak levels of tragedy, which made it cut even deeper. Izzie (Katherine Heigl), then an intern, developed a bond with the smooth-talking patient, and she ended up jeopardizing her career to move him up on the heart transplant list. Unfortunately, Denny still passed away after the transplant due to a blood clot, destroying the hearts of millions… poor Izzie included.
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