The Worst Epidemics Throughout History

Antonine Plague

The Antonine Plague occurred after Romans returned to the Empire after the campaigns in the East. The disease is believed to have been an early iteration of smallpox or measles. It is approximated that over 5 million people in the Roman empire died as a result of the untraceable disease. It tore through the towns from 165 to 180 AD, fifteen years of battling the affliction. 

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