Middlesex by Jeffrey Eugenides (2002)
This bildungsroman chronicles the effect of a mutated gene that spans three generations of a Greek family. Narrator and protagonist Cal Stephanides is a Grecian intersex man with 6-alpha-reductase deficiency, causing him to have feminine traits. The novel follows Stephanides’ family from their migration to the U.S. in 1922 to their societal assimilation, eventually culminating in an exploration of Cal’s own experiences as a person with a modified gender identity.
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